woman holding ice pack on ankle

Key Takeaways

  • Ice reliably reduces pain after an acute soft-tissue injury, but there is no high-quality evidence that icing accelerates tissue healing.
  • Dr. Gabe Mirkin, who coined the RICE protocol in 1978, publicly withdrew his support for it in 2014, stating that both ice and complete rest may delay healing rather than help it.
  • PEACE & LOVE, published in the British Journal of Sports Medicine in 2020, replaced RICE and reframes early inflammation as a necessary part of repair rather than something to suppress.
  • Frequent or prolonged icing — for example nine treatments within 48 hours — may delay recovery in more severe injuries, though brief icing for pain control remains reasonable.
  • A sham-controlled randomized trial in 60 physically active adults with grade I–II ankle sprains is testing PEACE & LOVE with versus without cryotherapy, with final follow-up due in August 2026.

The Protocol Everyone Learned Was Retracted by the Man Who Wrote It

In 1978, Dr. Gabe Mirkin published the RICE protocol — Rest, Ice, Compression, Elevation — in a sports medicine book, and it became the most repeated injury advice in the English language. In 2014 he withdrew it. 'Coaches have used my RICE guideline for decades,' he wrote, 'but now it appears that both ice and complete rest may delay healing, instead of helping.'

Twelve years later, the ice tubs are still everywhere and the question still comes up in nearly every acute injury visit at our Monroeville clinic. So here is the current answer, and the evidence behind it. A sham-controlled randomized trial in 60 physically active adults with acute grade I–II lateral ankle sprains — testing the PEACE & LOVE protocol with versus without cryotherapy,  has its final follow-up due this month, August 2026, and it should tighten this picture further.

Short answer: Ice relieves pain after an acute injury but does not speed healing, and prolonged icing may slow it. Current guidance, the PEACE & LOVE protocol,  recommends brief ice only for pain control, then protected early loading, compression, elevation, and movement to drive tissue repair.

The Science: Why Inflammation Isn't the Enemy

The original logic of RICE was that swelling and inflammation are damage, so suppressing them must help. We now understand inflammation as the opening phase of repair, not a complication of it. After a ligament or muscle tear, inflammatory cells clear damaged tissue and then switch phenotype to release growth factors — including insulin-like growth factor 1 — that trigger the rebuilding of collagen and muscle fiber. Blunting that signal early may delay the very process you want.

Ice works through vasoconstriction and slowed nerve conduction velocity. The slowed conduction is why it hurts less; the vasoconstriction is the problem. Reducing blood flow also reduces delivery of the repair cells and clearance of debris, and cold impairs lymphatic drainage, which can paradoxically leave more fluid in the tissue after the ice comes off. Studies show benefit in mild cases, but frequent or prolonged application — in one commonly cited example, nine treatments within two days — appears to delay recovery in more severe injuries.

In 2019, physiotherapists Blaise Dubois and Jean-François Esculier proposed a replacement framework, published in the British Journal of Sports Medicine in 2020. PEACE covers the first few days: Protect, Elevate, Avoid anti-inflammatory modalities, Compress, Educate. LOVE covers what follows: Load, Optimism, Vascularization, Exercise. Notice what changed. Ice is not in the acronym at all, complete rest is replaced by protection followed by early loading, and patient education and expectation are treated as active ingredients rather than pleasantries.

The load piece is the one that actually accelerates healing. Connective tissue is mechanosensitive — controlled mechanical stress tells collagen fibers which direction to align. Optimal loading means as much load as the tissue tolerates without increasing pain, introduced as early as safely possible. A randomized comparative study in adolescents with lateral ankle sprains found PEACE & LOVE outperformed PRICE on muscle strength and dynamic balance outcomes.

The 'A' in PEACE — avoid anti-inflammatories — needs a surgeon's caveat. The concern is that high-dose NSAIDs in the first days may blunt the same inflammatory signaling that starts repair, and there is animal and some human evidence for that in tendon and bone. In practice, short-course NSAIDs for a patient in real pain are a reasonable trade, and after certain procedures they are part of the protocol. This is a conversation to have with your surgeon, not a rule to apply blindly.

And to be clear about where ice still earns its place: it is a good analgesic. If ice lets you sleep, tolerate compression, or begin gentle movement sooner, it is helping you through pain control, not through healing. That is a real benefit, and it is also why post-operative cryotherapy protocols remain standard after many of the procedures I perform.

The Solution at POW PT

At POW PT, Dr. Josh Lombardi, DPT, CSCS, sees acute ankle and knee injuries under Pennsylvania's direct access rules -no physician referral required to start. The first visit is a triage: rule out fracture and high-grade instability, establish what the tissue can tolerate today, and start loading it.

Protection means limiting the movements that stress the injured structure while keeping everything else moving and not immobilizing the whole limb. Compression with an elastic wrap and elevation above heart level control swelling more effectively and more safely than repeated icing. Isometric contractions are introduced early because they are analgesic in their own right, which is often how we reduce reliance on ice within the first few days.

From there, loading is graded by symptom response rather than by a calendar. Pain during and after the session guides progression: a controlled increase that settles within 24 hours is acceptable, while pain that lingers means we backed off too little. Range of motion, then weight-bearing strength, then rate of force development, then change of direction. For a lateral ankle sprain we layer in balance and proprioceptive retraining early, because the neuromuscular deficit — not the ligament — is what predicts re-injury.

The Optimism in LOVE is not filler. Fear-avoidance and catastrophizing are independent predictors of poor outcome after ankle and knee injury. A patient who understands that early controlled loading is safe, and that hurting a little during rehabilitation is not the same as causing damage, recovers faster than one who has been told to rest and ice until it stops hurting. Explaining that is part of the treatment.

If pain, swelling, or giving-way persist beyond the expected window, we escalate. I evaluate for structural injury like osteochondral lesions, peroneal tendon pathology, syndesmotic involvement with weight-bearing CT and MRI, and we adjust the plan rather than repeating a protocol that is not working.

Frequently Asked Questions


Should I ice a sprained ankle?

You can ice for pain relief, but do not expect it to speed healing. Current guidance recommends brief icing, roughly 10 to 15 minutes at a time, only when needed for pain, and prioritizes protection, compression, elevation, and early controlled movement instead. If ice helps you sleep or tolerate early loading, it is doing useful work through pain control.

How long should you ice an injury?

If you choose to ice, limit it to 10 to 15 minutes per session with at least an hour between sessions, and always use a barrier between ice and skin. Longer or more frequent application does not improve outcomes and may delay recovery in more significant injuries. Most patients need ice only in the first 24 to 48 hours, for pain.

Is heat or ice better for an injury?

For a fresh injury in the first 48 hours, ice is the safer choice for pain control because heat can increase swelling. After the acute phase, heat is often more useful before activity to improve tissue extensibility and reduce stiffness. Neither one accelerates healing,  movement and progressive loading do that.

What does PEACE & LOVE stand for?

PEACE covers the first days after injury: Protect, Elevate, Avoid anti-inflammatory modalities, Compress, Educate. LOVE covers the phase after that: Load, Optimism, Vascularization, Exercise. The framework was proposed by physiotherapists Blaise Dubois and Jean-François Esculier and published in the British Journal of Sports Medicine in 2020 as a replacement for RICE.

Should I take ibuprofen for a sprain?

It depends. High-dose anti-inflammatories in the first days may blunt the inflammatory signaling that begins tissue repair, which is why PEACE advises avoiding them. In practice, a short course for significant pain is a reasonable trade-off, and after some surgical procedures NSAIDs are part of the protocol. Discuss it with your surgeon rather than applying a blanket rule.

Is it too late to ice after 48 hours?

Ice past 48 hours is not harmful, but it is rarely the most useful thing you can do. By that point the priority shifts to restoring motion, loading the tissue progressively, and retraining balance. If you are still relying on ice for pain at one week, that is a signal to have the injury re-evaluated rather than a reason to ice more.


Schedule an Evaluation

A sprain that still hurts, swells, or gives way after two weeks needs more than another ice pack. POW PT sees acute ankle and knee injuries under Pennsylvania direct access — no referral required. Call (412) 525-7692 or schedule online at orthoandwellness.com.

About the Author

Victor R. Prisk, MD is a board-certified orthopaedic surgeon specializing in foot, ankle, and sports medicine, and the CEO and Medical Director of Prisk Orthopaedics and Wellness, P.C. A former NCAA gymnast and competitive bodybuilder, he brings an athlete's understanding of training and recovery to surgical and non-surgical care. He is the author of The Leucine Factor Diet and directs the performance and rehabilitation programs at P.O.W. and P.O.W.Fit.